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| 3．Pulmonary Involvement of Hematological Disease |
| Yasuo Horikoshi |
| Division of Hematology and Oncology, Shizuoka Children’s Hospital |
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| Abstract |
| Children with hematological disease not uncommonly have pulmonary diseases, such as infiltration of leukemic cells and opportunistic infections. We should pay attention to the possible presence of pulmonary involvement during treatment of hematological disease and have proper physical examination. The pediatrician must be also aware of chemotherapeutic agents that can injure the lungs. High resolution CT (HRCT) should be done if chest X-ray, serologic test and microbiological tests are not diagnostic in patients with opportunistic infection. We also should decide on the necessity of invasive examination such as biopsy or bronchoscopy to make a definite diagnosis before deterioration of respiratory symptoms. We should pass the patient data to the radiologist and work together to make an accurate diagnosis. The study of HRCT would be done which diseases of childhood lung involvement with hematological disease have benefit or not. |
| Keywords：Hematological disease，HRCT，Pulmonary involvement |
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